Response to the Letter by Kosker et al. Entitled 'Choroidal Changes in Patients with Familial Mediterranean Fever'

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Choroidal Changes in Patients with Familial Mediterranean Fever.

study by Gundogan et al. We only included the patients with both clinically and genetically diagnosed FMF. Thus, we think this lowers the false positive risk and increases the sensitivity of the study. We are wondering whether all patients in Gundogan et al.’s study had MEFV gene mutations, and if so, whether there was any genotype-phenotype correlation? Because M694V mutations, especially in a...

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Genetic Analysis of Southwestern Iranian Patients with Familial Mediterranean Fever

Background: Familial Mediterranean fever (FMF) is an autosomal recessive genetic disorder characterized by recurrent episodes of self-limited fever and serosal tissues inflammation. Methods: To evaluate clinical symptoms and common genetic mutations in southwestern Iranian patients with FMF, 20 unrelated patients were enrolled in this study based on clinical criteria. A panel of 12 common ME...

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Reply to the Letter by Kaya et al. Entitled "Temperature Control Function of the Choroid May Be the Reason for the Increase in Choroidal Thickness During the Acute Phase of Familial Mediterranean Fever".

porters of this assumption are the positive correlations between the choroidal thickness and the indicators of inflammation such as erythrocyte sedimentation rate, fibrinogen and C-reactive protein levels. These findings suggest that an increase in the severity of the inflammatory reaction causes an increase in the choroidal thickness in patients with FMF. Additionally, some clinical studies al...

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Bone Mineral Density in Egyptian Children with Familial Mediterranean Fever

Background: Familial Mediterranean fever (FMF) has episodic or subclinical inflammation that may lead to a decrease in bone mineral density (BMD). The objective of this study was to assess BMD in Egyptian children with FMF on genetic basis.Methods: A cross sectional study included 45 FMF patients and 25 control children of both sexes in the age range between 3-16 years old. The patients were re...

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Comorbidities in patients with Familial Mediterranean Fever

Results The mean age was 27,5±16 (1-86) years. Our hospital mean follow-up period was 48,5±48 (1-352) months. 1343 patients (67,2%) had no comorbidities. 655 patients (32.8%) had comorbidities. Comorbidities were as follow: Appendectomy 30 (4,6%), cholecystectomy 20 (3,1%), acute rheumatic fever (2,4%), ankylosing spondylitis 155 (23,7%), juvenile idiopathic arthritis 31 (4,6%), rheumatoid arth...

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ژورنال

عنوان ژورنال: Ophthalmologica

سال: 2016

ISSN: 0030-3755,1423-0267

DOI: 10.1159/000443850